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Woman Age and IVF

The most important factor for your chance to get pregnant is your age. When you are above 36 years old, your chance of getting pregnant will naturally decrease by 50% compared to your mid-20’s.

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The reason is the decrease in your (chromosomal) healthy ovulation by age, especially after 36 age. If you have an early menopause story in your family (if any early menopause condition has been observed) (that’s you have a genetic predisposition to early menopause), or if you have received any chemotherapy and radiotherapy, then the number of eggs which complete their maturity process may get much lower. With aging, more chromosomal defects will be seen in your egg cells and as a result, this will cause non-implanted (that’s it cannot hold onto the womb), abnormal embryo formation or abortions at the earlier stages of pregnancy.

The women can protect their fertility from the drawbacks of the natural aging process through adopting a healthy life-style. At this point, it is really important to avoid smoking, drinking alcohol and caffeine, to make regular exercises and to maintain the healthy weight. However, protection from the drawbacks of the aging process is effective to some extent. Therefore, the best thing to do is to have a baby at an earlier age.

AMH (Anti-Mullerian Hormone) Test

Anti-Mullerian Hormone Test is a widely used blood test in determining the fertility of the woman. This hormone is an indication in determining the ovarian reserve (the amount of remaining eggs in the ovary) of the women. Although the ovary or ovarian reserve is not a criterion of the fertility, it is an important means of determining the potential of the fertility. AMH test will not provide any information about the quality of the eggs; however, it is a sign that provides the most accurate result in determining the ovarian reserve of the woman.

Risk of abortion increasing by age

The egg cell has 46 chromosomes just as the other cells of the body. However, this number needs to decrease by half, that’s to 23, for it to get together (match) with the chromosomes from the sperm cell. As the individual gets older, the egg cell splitting will not occur in a normal way as the genetic material (during egg splitting) is not equally distributed. This will cause genetic abnormalities ever-increasingly. This will unfortunately not only make it difficult for the older women to get pregnant, and also means to labor, but also to have an abortion at more increasing rates and to deliver a baby with genetic defects such as Down Syndrome.

Assisted Conception May be Helpful

With advanced reproductive technologies including in-Vitro fertilization (IVF: IVF Method) and other assisted conception choices, the chance of getting pregnant may increase. If you are between 36-40 ages, you can increase your chance of getting pregnant using in-vitro fertilization(IVF) and other assisted conception technologies. While the chance of conception is 5-8% within a month for the conception efforts by natural way that take more than 6 months, this rate (chance of conception) is 25-45% in In Vitro Fertilization (IVF) cycle. Many factors may affect the chance of individual success.

PreimplantationGeneticDiagnosis (PGD): Preimplantation Genetic Diagnosis (PGT) is a test method used in examination of the embryo in respect of certain genetic  and chromosomal defects before implantation. Thus, we can choose the embryo which will provide the highest chance of conception.

Protection of Fertility

The ages when a woman has the highest level of her fertility include her 20’s and the early 30’s. Today, it is possible to store the unfertilized eggs by freezing to use in the future. A relatively new technique, this provides the chance of getting pregnant for the women who are not suitable for conception or have some risks of conception due to a severe disease had.  However, it is not legal to apply this method in our country except for some special cases. For those women who will receive chemotherapy or radiotherapy because of cancer or similar problem, these therapies negatively affect the ovarian reserve. Therefore, such women are allowed to make their eggs frozen before chemotherapy or radiotherapy. However, it has not been proven that it (this technique) is useful for those women above 38 years old.

Impact of Man’s Age on Fertility

Even if the sperm quality gets reduced after 45 years old, the impact of the age on fertility is not so much important as with the women.  However, the risk of having a baby with a health problem (disabled or diseases) slightly increases for the men above 45 years old.