The development process the in-vitro fertilization method has passed over years:
The infertility problem is dated back to the beginning of human history and the wish of the infertile partners to have a baby through medical treatment is dated back to ancient times. The first successful result of the in-vitro fertilization treatments arising from such a need have only been able to be achieved in 1978. In those years, the human egg cell could be fertilized within an external environment and the miraculous solution for the medical world was implemented.
In in-vitro fertilization treatment, an artificial tube was implanted to a woman with obstructed tubes in 1968; however, there could not be achieved a successful result. Later in 1973, extracorporeal fertilization could be achieved; however, it will result in abortion, so there could not be achieved success.
Dr. Edwards and Dr. Steptoe worked together and for the first time, in 1978, achieved a success in in-vitro fertilization treatment in the UK.
The very first test-tube baby is Louise Brown
The in-vitro fertilization applications were first required as an opinion because of the obstructed tubes, and then, there has been made a huge progress in phases, and with today’s technology, theire development directions have been changed. In many genetic diseases of which presence is learned when it is still an embryo, the technical know-how has been achieved, which could change the direction of the treatment.
Which new techniques are implemented for in-vitro fertilization treatments today?
- Endometrial Coculture applications: Its benefit is scientifically controversial.
- Egg and embryo freezing procedures (Freezing)
- Making the embryo shell thinner (Assisted Hatching)
- IMSI technique in in-vitro fertilization treatments
- Acupuncture applications in IVF treatment for assistance purposes
- Preimplantation genetic diagnosis applications (PGD)
- Aiming at the selection of quality embryo through Metabolomics technique
- Genetic diagnosis methods through PGD and CGH techniques
Why the in-vitro fertilization treatments are preferred today?
- If the uterine ducts are obstructed and it has not been likely to get pregnant in normal ways
- In case of expectant fathers with troublesome sperm production or the sperm function insufficiency
- If the person have not had a baby normally in severe intra-abdominal adhesions in case of chocolate cyst
- If conception cannot be achieved because of the problems with the immune system
- In case of the infertility cases for reasons not exactly known
- For the partners with high rate of possibility to have a genetically distressed baby
- For the expectant mothers who have had recurring abortion cases
- If the partners could not have a baby previously using inoculation method, the in-vitro fertilization applications may be considered necessary.
- If the germ cells are required to be frozen because of various disorders and it needs to achieve conception at the proper time (as the cancer treatment will have an impact on the germ cells, the cells may be wanted to be frozen before starting the treatment. Likewise, if the sperm samples have been taken using surgical operations in males, these may be required to be frozen and used in the future.)
- For the partners in advanced ages who cannot get pregnant in its natural form, the in-vitro fertilization treatments may be given priority.
Which phases have been set as criteria in the IVF treatments so far?
- At the first phase, examination and general assessment of the patients will be performed.
- At the second phase, the necessary facilities for the stimulation of the ovaries properly and the development of the egg will be provided.
- At the third phase, the eggs will be collected,
- At the fourth phase, the fertilization will be enabled,
- Finally, at the fifth phase, the embryo will be transferred into the mother’s womb.